The Chemistry and Biological Activity of Synthetic and Natural Compounds

 

 

 

FINAL PROGRAM
of the Conference CBC2015

 

THE CHEMISTRY OF  HETEROCYCLIC COMPOUNDS. MODERN ASPECTS

 

August 31 - September 3, 2015

 

(Beloselsky-Belozersky Palace,

Russia, Saint-Petersburg, 41 Nevsky prospect)

 

 

 

Sunday, August 30, 2015

 

16:30–21:00 Registration (the Lobby of the "N-Prospect" Art Gallery)

 

The registration of participants will be held in the Lobby of the "N-Prospect" Art Gallery
(Saint-Petersburg, 78 Nevsky prospect).

 

All participants of the conference should have passports.

 

 


Monday, August 31, 2015

 

08:00–9:00 Registration (The Gallery of Beloselsky-Belozersky Palace, 41 Nevsky prospect)

 

 

9:00 Opening Ceremony (Oak Hall, Beloselsky-Belozersky Palace)

Opening Keynote Address by Academician of the Russian Academy of Natural sciences Victor G. Kartsev, Chairman of the Organizing committee, Chairman of the "Scientific Partnership" Foundation

 

Greetings by honorary delegates of the conference

 

9:30 Awarding ceremony of the Gold Medal "100th anniversary of Prof. A.N. Kost"

and of the International ScientificPartnership Foundation's awards

 

 

Scientific Program

 

Keynote Lectures

 

Session Chairpersons: Prof. van der Plas H., Prof. Charushin V.N.

10:30–11:10

Kartsev V.G. (Russia)

Targeted modification and virtual screening of natural products

11:15–11:45

Stanovnik B. (Slovenia)
Enaminones in the thermal [2+2]cycloadditions. Synthesis of heterocyclic systems, ring expansion reactions, rearrangements and other transformations

 

12:00–13:15

Lunch (Restaurant "Dve palochki", 47 Nevsky prospect)

 

 

Plenary Lectures

 

Session Chairpersons: Prof. Stanovnik B., Prof. Shibata N.

13:15–13:35

Charushin V.N., Chupakhin O.N. (Russia)
Direct nucleophilic C-H functionalization of heteroaromatics. Transition metal-catalyzed and tm-free (SNH) reactions

13:40–14:00

Minkin V.I. (Russia)
Bistable spiroheterocyclic compounds for molecular photonics, spintronics and chemosensorics

14:05–14:25

Saxena A.K. (India)
Chemistry of octa- and decahydropyrazinopyridoindoles: A new class of antipsychotic agents

14:30–14:50

Mąkosza M. (Poland)
Reactions of nucleophiles with nitroarenes - versatile tools in synthesis of indoles

 

14:50–15:30

Coffee Break (State Dining Room, Beloselsky-Belozersky Palace)

 

 

Oral Presentations

 

Session Chairpersons: Prof. Saxena A.K., Prof. Chupakhin O.N.

15:30–15:45

Attanasi O.A. (Italy)
Cultivating over thirty years the passion to build heterocycles from1,2-diaza-1,3-dienes: The force of imagination

15:50–16:05

Traven' V.F. (Russia)
New photosensitive coumarin derivatives: Synthesis and application for information optical recording

16:10–16:25

Geronikaki A., Eleftheriou P., Balalaie S. (Greece)
Study of inhibition of the protein phosphatises PTP1B, LAR and HSP-2 by novel 3-[(fyran-2-yl)methyl]-2-phenyl thiazolidine-4-one derivatives and 2,4-dimethyl-4,12b-dihydro-1H,7H-chromeno[40,30:4,5]pyrano-[2,3-d]pyrimidine-1,3(2H)-dione as potent drugs for the treatment of diabetes and obesity

16:30–16:45

Patrushev S.S., Shults E.E. (Russia)
Synthesis and biological activity of
13-(2,6-dioxo-2,3-dihydro-1H-purine-8-yl)eudesmanolides

16:50–17:05

Saxena M. (India)
Synthesis of primaquine glycoconjugates at physiological pH as potential tissue-schizontocidal antimalarial agents

17:10–17:25

Przheval'skii N.M., Laipanov R.K., Tokmakov G.P., Rozhkova E.N. (Russia)

Multicomponent synthesis of new derivatives of pyridones and pyrimidinones

17:30–17:45

Nelina-Nemtseva J.I., Nguyen T.L.H., Gulevskaya A.V. (Russia)
Nucleophilic and electrophilic cyclizations of 2,3-dialkynylquinoxalines and their nitrile analogs as a method for polynuclear heterocyclic compounds synthesis

 

 

18:30–20:00

Welcome Cocktail Party
(State Dining Room, Beloselsky-Belozersky Palace, 41 Nevsky prospect)

 

 


Tuesday, September 1, 2015

 

 

Plenary Lectures (Oak Hall, Beloselsky-Belozersky Palace)

 

Session Chairpersons: Prof. Attanasi O.A., Prof. Yus M.

8:30–8:50

Maienfisch P. (Switzerland)
Synthesis of nitroimino-substituted heterocycles and their applications in insecticide discovery

8:55–9:15

Pozharskii A.F., Filatova E.A., Kachalkina S.G. (Russia)
Recent advances in indole cyclizations of o-alkynyl- and o-acylanilines

9:20–9:40

Spinelli D. (Italy)
The Boulton-Katritzky reaction: Remembering a friend and a magister

9:45–10:05

Petrosyan V.S., Shuvalova E.A. (Russia)
Heterocyclic cyanotoxins - priority stressors of man and the environment

10:10–10:30

Poroikov V.V., Filimonov D.A., Lagunin A.A., Gloriozova T.A., Gawande D., Goel R. (Russia)
Libraries of natural and synthetic compounds as a source of new lead compounds

 

10:30–10:50

Coffee Break (State Dining Room, Beloselsky-Belozersky Palace)

 

 

Plenary Lectures

 

Session Chairpersons: Prof. Geronikaki A., Prof. Mamedov V.A.

10:50–11:10

Shibata N. (Japan)
Synthesis of phthalocyanines having a pentafluorosulfanyl substitution at peripheral positionsnatural product synthesis

 

 

Oral Presentations

 

11:15–11:30

Abdou W., Kamel A., Shaddy A. (Egypt)
Innovation of natural product-mimics as novel anti-tumor active agents based on molecular modeling techniques

11:35–11:50

Lipeeva A.V., Shults E.E. (Russia)
New approaches to the synthesis of 2-substituted derivatives of psoralens

 

 

12:00–13:15

Lunch (Restaurant "Dve palochki", 47 Nevsky prospect)

 


Oral Presentations

 

Session Chairpersons: Prof. Knölker H.-J., Prof. Pozharskii A.F.

13:20–13:35

Yus M. (Spain)
Enantioselective addition of organomagnesium reagents to carbonyl compounds: Chiral 2-substituted tetrahydropyrans

13:40–13:55

Mikhailovskii A.G., Surikova O.V., Syropyatov B.Ya., Yusov A.S. (Russia)
Roads of constructing for new biologically active compounds in 3-methyl- and 3,3-dialkylisoquinoline series

14:00–14:15

Mamedov V.A. (Russia)
Ring transformations of functionalized quinoxalinones towards benzimidazoles and benzimidazolones

14:20–14:35

Konovalova V.V., Shklyaev Yu.V., Maslivets A.N. (Russia)
Chemical modifications of heterocyclic enamines by the action of five-membered O- and N-2,3-dioxoheterocycles

14:40–14:55

Medvedev J.J., Semenok D.V., Nikolaev V.A., Rodina L.L. (Russia)
A new powerful approach for the synthesis of 4,5-diaryl-3(2H)furanones -
a promising inhibitors for cyclooxygenase-2

 

  

 

18:30–21:30

Sightseeing bus tour of Saint-Petersburg

 



Tuesday, September 1, 2015

 

 

15:20–17:50

Poster Session (The Gallery of Beloselsky-Belozersky Palace)


Poster presentations are posted at 10.30.
Authors are required to be present at their stands during
the coffee breaks and from 15.20 to 17.50.

 

Poster nos.

List of Posters

1

Aimakov O.A. (Kazakhstan)
Certain derivatives of the alkaloid anabasine and their properties

2

Aksenov A.V., Aksenov N.A., Smirnov A.N., Orazova N.A., Aksenova I.V.,
Rubin M.A. (Russia)
Synthesis of acridines via diarylamination of arenes

3

Berestovitskaya V.M., Serebryannikova A.V., Lapshina L.V., Efremova I.E. (Russia)
New pyrazolidine- and isoxazolidine-containing bicyclic compounds with nitrosulfolane ring

4

Elossaily Y.A., Zaki R.M., Metwally S.A., Gaber T.A. (Egypt)
Synthesis, reactions and spectral characterization of some new chromeno[2,3-d]pyrimidine compounds

5

Kabanova M.V., Chirkova Zh.V., Filimonov S.I., Abramov I.G. (Russia)
Effective inhibition of monoamine oxidase by new 3-chlorine-substitutedindole-5,6-dicarbonitriles

6

Khalyavina Yu.G., Gornostaev L.M., Lavrikova T.I., Kalashnikova I.V.,
Kiseleva N.V., Chernyshev V.V. (Russia)
Synthesis and functionalization of oximes 1Ν-naphtho[2,3-d][1,2,3]triazole-4,9-diones and their N-oxides

7

Khalymbadzha I.A., Fatykhov R.F., Deev S.L., Shestakov T.S., Chupakhin O.N., Kartsev V.G. (Russia)
Direct hetarylation of natural benzopirones with azines. Reaction of 5,7-dihydroxy chromones and coumarins with nitroquinoxalone and 3-methylthio-1,2,4-triazine

8

Khalymbadzha I.A., Fatykhov R.F., Deev S.L., Shestakov T.S., Chupakhin O.N., Kartsev V.G. (Russia)
Modification of coumarins with pyrimidines. Simple synthesis of coumarin derivatives of 2,4-diazabicyclo[3.3.1]nonane

9

Kharitonov Yu.V., Shults E.E. (Russia)
Synthesis of macroheterocyclic compounds with a furan bridge possessing structural fragments of 1,2,3-triazoles and natural diterpenoids

10

Krapivin G.D., Kanischeva E.A., Vasilin V.K., Stroganova T.A. (Russia)
3-Azidothieno[2,3-b]pyridines thermolysis as a synthetic path to fused and peri-annelated systems

11

Mikhailovskii A.G., Pantyukhin A.A., Aleksandrova G.A., Makhmudov R.R., Pershina N.N., Balandina S.Yu. (Russia)
Bicyclic 1,3-diketones in synthesis of biologically active heterocycles

12

Mikhal'chuk A.L., Gulyakevich O.V. (Belarus)
Synthesis of CN-condensed derivatives of isoquinoline by the annelation of 3,4-dihydroisoquinolines with a-acyl-b-cyclandiones - [4+2]-cyclocondensations

13

Mikhal'chuk A.L., Gulyakevich O.V. (Belarus)
Synthesis of CN-condensed derivatives of isoquinoline[3+3]-cyclocondensations of 1-alkyl-3,4-dihydroisoquinolines with 1,3-dielectrophiles (b-ketoesters 2-aminomethylenecyclandiones, ...)

14

Mukusheva G.K., Baisarov G.M., Zhanymkhanova P.Zh., Toigambekova N.N., Adekenov S.M. (Kazakhstan)
Synthesis of new derivatives on the basis of some flavonoids

15

Selikhova N.Yu., Makarov A.G., Makarov A.Yu., Slizhov Yu.G., Malkov V.S., Zibarev A.V. (Russia)
Synthesis and functionalization of the fluorinated derivatives of quinoxaline

16

Sirakanyan S.N., Hovakimyan A.A., Noravyan A.S. (Armenia)
New heterocyclic system: 10-alkyl-7-amino-8,9,10,11-tetrahydro-5H-pyrazolo[3,4-c][1,2,4]triazolo[3,4-a]-2,7-naphthyridines

17

Sirakanyan S.N., Hovakimyan A.A., Spinelli D., Geronikaki A., Noravyan A.S., Harutyunyan A.S. (Armenia)
Synthesis and chemical properties of the 7-alkyl(aryl)-1-azido-3-chloro-4-cyano-5,6,7,8-tetrahydro-2,7-naphthyridines

18

Sirakanyan S.N., Hovakimyan A.A., Spinelli D., Geronikaki A., Noravyan A.S., Harutyunyan A.S. (Armenia)
Synthesis of furo- and thieno[2,3-e]tetrazolo[1,5-c]pyrimidines

19

Stroganova T.A., Vasilin V.K., Kovalenko G.A., Krapivin G.D. (Russia)
Furan ring recyclization in N-(5-methylfur-2-ylethyl)-3-aminothieno[2,3-b]pyridine-2-carboxamides

20

Vasilin V.K., Stroganova T.A., Krapivin G.D. (Russia)
Interaction of pyridothieno[1,4]diazepines with ketenes

21

Velikorodov A.V. (Russia)
Synthesis of oxygen-containing heterocycles with carbamate function

22

Velikorodov A.V., Stepkina N.N., Melent'eva E.A., Starikova A.A., Ionova V.A. (Russia)
Synthesis of spiro compounds from 11H-indeno[1,2-b]quinoxalin-2-one

23

Zhukova N.A., Galimullina V.R., Zamaletdinova A.I., Nigmatullina L.Sh.,
Latypov Sh.K., Mamedov V.A. (Russia)
Quinoxalinone-benzimidazole rearrangement: Expeditious entry to diverse quinoline derivatives with the benzimidazole moieties

24

Zhukova N.A., Zamaletdinova A.I., Samigullina A.I., Bazanova O.B.,
Latypov S.K., Mamedov V.A. (Russia)
Efficient access to N-pyrrolyl-benzimidazol-2-ones and their aza-analogues via a novel rearrangement

 

 

 


Wednesday, September 2, 2015     (For Foreign Delegates)

 

 

9:00

Social events for foreign guests
(a visit to the Hermitage, entertainment program, etc.)

 

12:00–13:00

Lunch (Restaurant "Dve palochki", 47 Nevsky prospect)

 

 

19:00–20:30

Welcome Cocktail Party in the "N-Prospect" Art Gallery
(78 Nevsky prospect)

 

 

 

 

Wednesday, September 2, 2015
(Session
For Russian and CIS Delegates.
Working language is Russian)

(Oak Hall, Beloselsky-Belozersky Palace)

 

 

Plenary Lectures

 

Session Chairpersons: Prof. Mikhal'chuk A.L., Prof. Gulevskaya A.V.

8:30–8:50

Rusinov V.L., Chupakhin O.N., Charushin V.N., Kiselev O.I. (Russia)
Novel class of antiviral compounds - azolo-1,2,4-triazimes

8:55–9:15

Adekenov S.M. (Kazakhstan)
Searching for new heterocyclic compounds among natural flavonoids and alkaloids

9:20–9:40

Aksenov A.V., Aksenov N.A., Smirnov A.N., Aksenova I.V., Rubin M.A. (Russia)
"Intelligent" reaction media in synthetic modifications of heterocyclic compounds

9:45–10:05

Shchekotikhin A.E., Preobrazhenskaya M.N. (Russia)
Chemistry and biology of antitumor heteroareneanthracenediones

10:10–10:30

Shults E.E. (Russia)
Synthesis, transformations and biological activity of tetradecahydronaphtho[2,1-d]indoles

 

10:30–10:50

Coffee Break (State Dining Room, Beloselsky-Belozersky Palace)

 

 

Oral Presentations

 

Session Chairpersons: Prof. Rusinov V.L., Prof. Shchekotikhin A.E.

10:55–11:10

Berestovitskaya V.M. (Russia)
The synthesis of heterocyclic compounds based on highly electrophilic nitroalkenes

11:15–11:30

Mustafin A.G., Gimadieva A.R., Abdrakhmanov I.B. (Russia)
Synthesis and biological properties of novel uracil derivatives

11:35–11:50

Velikorodov A.V., Zubkov F.I. (Russia)
Synthesis of new azaheterocycles with carbamate function through[3+2]-cycloaddition reaction

 

12:00–13:15

Lunch (Restaurant "Dve palochki", 47 Nevsky prospect)

 

 

Oral Presentations

 

Session Chairpersons: Prof. Berestovitskaya V.M., Prof. Velikorodov A.V.

13:20–13:35

Krasnov K.A., Kartsev V.G. (Russia)
T-reactions of cyclic b-dicarbonyl compounds: Stereochemical aspects

13:40–13:55

Saloutin V.I., Scherbakov K.V., Burgart Ya.V., Chupakhin O.N. (Russia)
4-Hydroxypolyfluorocoumarins in organic synthesis

14:00–14:15

Shikhaliev Kh.S., Didenko V.V., Ledenyova I.V. (Russia)
Chemistry of pyrazole-3(5)-diazonium salts

14:20–14:35

Mikhal'chuk A.L., Gulyakevich O.V. (Belarus)
Ternary [3+2+1]-cyclocondensations of 1-alkyl-3,4-dihydroisoquinolines with methylene active compounds and methyleneating reagents in the synthesis of the azangulyar heterocycles

 

14:40–14:55

Rodina L.L. (Russia)
Chemistry of the excited states of diazocarbonyl compounds - new data

15:00–15:15

Gornostaev L.M., Arnold E.V., Krukovskaya I.S., Kuznetsova A.S.,
Lavrikova T.I., Nuretdinova E.V., Rukovets T.A., Khalyavina Yu.G. (Russia)
Synthesis of polycyclic azoles and azines of aminoquinones

15:20–15:35

Ukrainets I.V., Petrushova L.A., Bereznyakova N.L., Dzyubenko S.P. (Ukraine)
Synthesis, chemical transformations and biological properties of alkyl 1-R-4-hydroxy-2,2-dioxo-1H-2l6,1-benzothiazine-3-carboxylates

15:40–15:55

Vafina G.F., Uzbekov A.R., Galin F.Z. (Russia)
Synthesis of hetero-"bird cage" compounds on the basis of quinopimaric acid

 

 

19:00–20:30

Welcome Cocktail Party in the "N-Prospect" Art Gallery
(78 Nevsky prospect)

 

 



Thursday, September 3, 2015

 

 

Plenary Lectures (Oak Hall, Beloselsky-Belozersky Palace)

 

Session Chairpersons: Prof. Maienfisch P., Prof. Petrosyan V.S.

8:30–8:50

Hesse R., Julich-Gruner K.K., Kataeva O., Kumar V.P., Knölker H.-J. (Germany)
Total synthesis of biologically active carbazole alkaloids

8:55–9:15

Maes B.U.W. (Belgium)
Sustainable synthesis of isothiourea and their application in organic synthesis

9:20–9:40

Nishiwaki N. (Japan)

A new synthetic approach to aza-heterocyclic compounds using pseudo-intramolecular process

9:45–10:05

Shklyaev Yu.V., Rozhkova Yu.S., Galata K.A., Vshivkova T.S., Morozov V.V., Perevoshchikova A.N. (Russia)
Three component synthesis of nitrogen-containing heterocycles: Practical application of appearing functions

 

10:10–10:40

Coffee Break (State Dining Room, Beloselsky-Belozersky Palace)

 

 

Oral Presentations

 

Session Chairpersons: Prof. Poroikov V.V., Prof. Aksenov A.V., Prof. Shults E.E.

10:45–11:00

Tenora L., Galeta J., Kryštof V., Nencka R., Potácek M. (Czech Republic)
Dihydropyrrolo[1,2-b]pyrazoles: Synthesis of new derivatives and their biological evaluation

11:05–11:20

Nájera C., Sansano J.M., Mancebo-Aracil J., Cayuelas A., Castello L.M. (Spain)
Synthesis of pyrrolizidines and indolizidines by multicomponent 1,3-dipolar cycloadditions of azomethine ylides

11:25–11:40

Chugunova E.A., Voloshina A.D., Mukhamatdinova R.E., Kulik N.V., Serkov I.V., Burilov A.R., Zobov V.V. (Russia)
Superelectrophilic benzofuroxans - perspective reagents for the synthesis of new types of biological active heterocyclic compounds

11:45–12:00

Klochkov S.G., Pukhov S.A., Afanasieva S.V. (Russia)
Sesquiterpene lactones as multitarget substances with antitumor effect

   

 

12:00–13:00

Ρlosing Ceremony

 

15:30–17:30

Final extended tour with champagne on the canals of Saint-Petersburg

 

18:00

Departure