InterBioScreen Monograph Series
SELECTED METHODS
FOR SYNTHESIS AND MODIFICATION
OF HETEROCYCLES
THE CHEMISTRY AND BIOLOGICAL
ACTIVITY
OF NATURAL INDOLE SYSTEMS
Edited by Prof. V.G. Kartsev
 |
International Editorial Board: Prof. Bergman
J. (Sweden) |
4
Volume, 352 pages,
Moscow: Published by the International Charitable Foundation Scientific Partnership
(ICSPF), 2005
|
This volume in the series Selected Methods for Synthesis and Modification of Heterocyles—published by InterBioScreen Ltd. and the International Charitable Foundation Scientific Partnership—is devoted to the chemical behavior and biological activity of naturally occurring indole systems.
The chemistry of indole alkaloids
has been under research since the 50s. At that time, the number of such alkaloids
did not exceed a mere hundred. To date, indole alkaloids have emerged as probably
the largest class of alkaloids (over 1200 compounds) extracted from more than
40 families of plants, micro-, and marine organisms.
This is Part 1 of the vast material on the chemistry of various indole alkaloids selected by the Editorial Board for publication in the series. Volume 4 contains reviews of the state-of-the-art chemistry of indole alkaloids contributed by worldwide recognized experts in the chemistry and biological activity of indole systems, which makes the book useful and instructive for a wide circle of readers.
Part 2, devoted to natural indole systems, is planned to appear in Volume 5 of the series. It will cover the available data on more than 900 alkaloidsbearing the indole moiety, their biosynthesis, stereochemistry, biological activity, mechanism of action, and will also discuss some aspects of total synthesis of indole alkaloids.
Volumes 1, 2 in the series Selected Methods for Synthesis and Modification of Heterocyles appeared in 2003. Volume 1 is a collection of reviews on the synthesis and modification of nitrogen-containing heterocycles while Volume 2, of oxygen- and sulfur-containing heterocycles.
Volume 3 (appeared in 2004) is devoted to the chemistry of synthetic indole systems and covers a wide range of indoles, from simple representatives of this class to more complicated (largely synthetic) condensed systems.
Volume 4 and the forthcoming Volume 5 are a logical continuation of our previous publications focused on natural indole systems. Symbolically, this volume is being issued in the year of the 90th Anniversary of birthday of my great and dear Teacher, Prof. A.N. Kost, who worked at Moscow State University and greatly contributed to the chemistry of indole and its derivatives.
In 2006–2007, we are planning to publish the next volumes that will overview the most recent advances in the chemical behavior and biological activity of carbolines (Volume 6), isoquinolines (Volume 7), and quinolines (Volume 8).
V. Kartsev
Moscow, December 2005
| Aripova S.F., Kartsev V.G.1, Khuzhaev V.U. Natural simple indole alkaloids |
7 |
| Bölcskei H. Ibogamine/catharanthine-type indole alkaloids and their synthetic derivatives (Part I) |
38 |
| Bölcskei H. Ibogamine/catharanthine-type indole alkaloids and their synthetic derivatives (Part II) |
49 |
| Bölcskei H. Vinblastine-type indole-indoline alkaloids and their derivatives |
71
|
| Bölcskei H. Ergot alkaloids and their synthetic derivatives |
108
|
| Fraschini F., Demartini G., Lucini V., Spadoni G., Bedini
A., Guidi T., Tarzia G., Esposti D. Synthesis and biology of melatonin and related indole analogs |
132
|
| Knölker H.-J., Reddy K.R. Total synthesis of furocarbazole alkaloids |
166
|
| Lakatosh S.À., Preobrazhenskaya Ì.N. Synthesis of indolo[2,3-a]pyrrolo[3,4-c]carbazoles, related bis(indol-3-yl)maleimides, and their analogs |
182
|
| Shults E.E., Tolstikov G.A. Tremorgenic indole alkaloids |
241
|
| Stonik V.A., Radchenko O.S. Marine alkaloids, including bioactive indole derivatives |
287
|
|
|
|
| Author index |
336 |