The Chemistry and Biological Activity of Synthetic and Natural Compounds

 

 

 

FINAL PROGRAM
of the Conference

 

MODERNASPECTSOFCHEMISTRYOFHETEROCYCLES

 

August 26, 2010

 

(Beloselsky-Belozersky Palace,

Russia, Saint-Petersburg, 41 Nevsky prospect)

 

 

 

Sunday, August 1, 2010

 

16:0021:00 Registration (the Lobby of the "N-Prospect" Art Gallery)

 

The registration of participants will be held in the Lobby of the "N-Prospect" Art Gallery
(Saint-Petersburg, 78 Nevsky prospect).

 

All participants of the conference should have passports.

 

 


Monday, August 2, 2010

 

08:009:45 Registration (The Gallery ofBeloselsky-Belozersky Palace)

 

 

9:30 Opening Ceremony (Oak Hall, Beloselsky-Belozersky Palace)

Opening Keynote Address by Prof. Victor G. Kartsev, Chairman of Organizing committee,

Chairman of "Scientific Partnership" Foundation

 

Greetings by honorary delegates of the conference

 

10:00 Presentation ceremony of the Medal "In memory of Professor A.N. Kost"

and the International ScientificPartnership Foundation's awards

 

 

Scientific Program

 

Keynote Lectures

 

Session Chairpersons: Prof. Stanovnik B., Prof. Abu-Orabi S.T., Prof. Zefirov N.S.

10:4011:10

van der Plas H. (the Netherlands)

Selected reactions in the cyclisation of heterocycles. Cycloalkenopyridines by ring transformation of diazines and triazines

11:1511:45

Kartsev V.G., Zubenko A.A. (Russia)

New rearrangements of natural and synthetic hemiaminals

 

11:5012:10 Coffee Break(State Dining Room, Beloselsky-Belozersky Palace)


 

Keynote Lectures

 

Session Chairpersons: Prof. Mąkosza M., Prof. Preobrazhenskaya .N.

12:1512:45

D'Anna F., Frenna V., Lanza C.Z., Spinelli D. (Italy)

On the mononuclear rearrangement of heterocycles

12:5013:20

Stanovnik B. (Slovenia)

From b-dimethylamino-a-acylamino-a,b-didehydro acid derivatives and related enaminones via heterocycles and heterocyclic amino acids to indole alkaloids

 

13:3014:25 Lunch

 


Plenary Lectures

 

Session Chairpersons: Prof. van der Plas H., Prof. Spagnolo P.

14:3015:00

Zefirov N.S., Matveeva E.V. (Russia)

Computer and synthetic approaches to novel heterocyclic compounds

15:0515:35

Mąkosza M., Loska R. (Poland)

Synthesis of perfluoroalkyl heterocycles via nucleophilic substitution of hydrogen

15:4016:10

Preobrazhenskaya .N. (Russia)

Chemical modification of macrolide antibiotics of oligomycin and amphothericin groups

16:1516:45

Affortunato F., Degennaro L., Florio S., Giovine A., Luisi R., Mansueto R., Musio B. (Italy)

New horizons in the chemistry of aziridines

 

 

17:0018:30 Welcome Cocktail Party

(State Dining Room, Beloselsky-Belozersky Palace, 41 Nevsky prospect)

 

 


Tuesday, August 3, 2010

 

 

9:009:30

Awarding ceremony of Gold Badge of International Scientific Partnership Foundation continued (Oak Hall, Beloselsky-Belozersky Palace)

 

Plenary Lectures (Oak Hall, Beloselsky-Belozersky Palace)

 

Session Chairpersons: Prof. Attanasi O.A., Prof. Poroikov V.V.

9:3510:05

Vasilevsky S.F., Baranov D.S. (Russia)

New multichannel reactions of acetylenes: an unexpected rearrangement with insertion of nitrogen atom between two acetylenic carbons

10:1010:40

Attanasi O.A. (Italy)

Cultivating over thirty years the passion to build heterocycles from
1,2-diaza-1,3-dienes: the force of imagination

10:4511:15

Charushin V.N., Rusinov V.L., Ovchinnikova I.G., Fedorova O.V.,
Verbitsky E.V., Slepukhin P.A., Chupakhin O.N. (Russia)

Use of tandem and cascade reactions for the synthesis of heterocyclic compounds

 

11:2011:40 Coffee Break (State Dining Room, Beloselsky-Belozersky Palace)

 

 

Oral Presentations

 

Session Chairpersons: Prof. Geronikaki A., Prof. Vasilevsky S.F.

11:4512:05

Arseniyadis S. (France)

From complex oxygen heterocycles to stereodefined carbocycles and chemoselectivity: the domino and chiral pool approaches for biologically active natural product synthesis

12:1012:30

Koutentis P.A., Gollner A., Lo Re D., Loizou G. (Cyprus)

New routes to azafluoranthenes

12:3512:55

Mikhailovskii A.G., Surikova O.V., Polygalova N.N., Aliev Z.G.,
Vakhrin M.I. (Russia)

Cyclic azomethines and enamines f 3,4-dihydroisoquinolinium series in heterocyclic synthesis

 

13:0014:25 Lunch



Oral Presentations

 

Session Chairpersons: Prof. López Calahorra F., Prof. Charushin V.N.

14:3014:55

Rádl S., Stach J. (Czech Republic)

Synthesis of impurities and/or degradation products of selected heterocyclic drugs as an integral part of the API development

15:0015:20

Bennamane N., Nedjar-Kolli B., Geronikaki A., Eleftheriou P., Kaoua R., Boubekeur K., Hoffman P., Chaudhaery S.S., Saxena A.K. (Greece)

N-substituted [phenyl-pyrazolo]-oxazin-2-thiones as COX-LOX inhibitors: influence of the replacement of the oxo-group with thioxo-group on the COX inhibition activity of N-substituted pyrazolo-oxazin-2-ones

15:2515:45

Traven' V.F., Kondratova N.A., Solov'eva N.P. (Russia)

Unusual reactions of 2,3-dihydrofuro[3.2-c]coumarin-3-one, its arylidene and cinnamylidene derivatives with arylhydrazines

15:5016:10

Erdogan E., Kilic H., Bayindir S., Saracoglu N. (Turkey)

Synthesis of possible biological active aza-substituted indoles

 

16:1016:30 Coffee Break (State Dining Room, Beloselsky-Belozersky Palace)

 

 

Oral Presentations

 

Session Chairperson: Prof. Álvarez M.

16:3516:55

Latorre S., Moreira I. de P.R., Bofill J.M., López Calahorra F. (Spain)

Benzothiazole-acridine amines, a new family of multifunctional molecules: from the molecular level to the organic material

17:0017:20

Belovodskii A.V., Shults E.E., lstikov G.. (Russia)

Palladium-catalyzed arylation of eudesmane type methylene-lactones and their biological activity

 

 

18:3020:30 Sightseeing tour of Saint-Petersburg




Wednesday, August 4, 2010

 

9:009:30

Awarding ceremony of Gold Badge of International Scientific Partnership Foundation continued (Oak Hall, Beloselsky-Belozersky Palace)

 

Plenary Lectures (Oak Hall, Beloselsky-Belozersky Palace)

 

Session Chairpersons: Prof. Spinelli D., Prof. Pozharskii A.F.

9:3510:05

Yamamoto Y. (Japan)

Coinage metal catalyzed heterocycle synthesis

10:1010:40

Poroikov V.V., Filimonov D.A., Lagunin A.A., Gloriozova T.A. (Russia)

Computer-aided prediction of biological activity for natural compounds and their derivatives

10:4511:20

Martin R., Agarwal S., Jäger A., Böhl M., Richter S., Tsiavaliaris G., Fedorov R., Manstein D.J., Gutzeit H.O., Knölker H.-J. (Germany)

Specific inhibitors of myosin ATPase via silver-catalyzed synthesis of pyrroles

 

11:2511:55 Coffee Break (State Dining Room, Beloselsky-Belozersky Palace)

 

 

Oral Presentations

 

Session Chairpersons: Prof. Knölker H.-J., Prof. Gulevskaya A.V.

12:0012:20

Abdou W.M., Khidre M.D., Sediek A.A. (Egypt)

The design and synthesis of sulfur and nitrogen containing bisphosphonic acids and their role in oncology

12:2512:45

Petrov M.L., Androsov D.A. (Russia)

New approaches towards benzofurans, indoles and benzothiophenes

12:5013:10

Bölcskei H., Gere A., Domány Gy. (Hungary)

Synthesis of diphenyl-triazole and diphenyl-triazine derivatives with COX-2 inhibitory effect

 

13:1514:45 Lunch

  

 

Oral Presentations

 

Session Chairpersons: Prof. Arseniyadis S., Prof. Traven' V.F.

14:5015:10

Nawwar G. (Egypt)

Simple synthesis of biologically active heterocycles utilizing
3-oxoalkanocarboxylates

15:1515:35

Gulevskaya A.V., Tyaglivy A.S., Nguen T.L. Huong (Russia)

Nucleophile-induced cyclizations of mono- and dialkynylpyrazines and pyridazines

15:4016:00

Ganoub N. (Egypt)

Application of phosphorus carbanions in heterocyclic synthesis. An approach to pharmacologically important N- and O-heterocycles and the relevant phosphonate derivatives

 

16:0516:25 Coffee Break (State Dining Room, Beloselsky-Belozersky Palace)

 

 

Oral Presentations

 

Session Chairpersons: Prof. Balci M., Prof. Yamamoto Y.

16:3016:50

Balci M. (Turkey)

Development of new synthetic methodologies for indole, benzoazepinone, furopyrimidinone and furopyrrolone skeleton

16:5517:15

Gautam N., Sharma M.K., Gupta S., Ajmera N., Gautam D.C. (India)

Synthesis and biological evaluation of 10H-phenothiazine,
4H-1,4-benzothiazines and their ribofuranosides

 

 


8:0017:00 Poster Session 1 (poster nos. 120)

(The Gallery of Beloselsky-Belozersky Palace)

 

Poster nos.

Poster Details

1

Borzenko A.O., Schafer L.L. (Canada)

Diastereoselective synthesis of substituted piperazines using hydroamination catalysis

2

Botoshansky M., Belakhov V., Goldstein D., Ionin B.I. (Israel)

Design, synthesis, crystal structure and biological evaluation of novel stabilized derivatives of ascorbic acid

3

Dodonova J., Tumkevicius S. (Lithuania)

Study on the Suzuki reaction of halopyrrolo[2,3-d]pyrimidines

4

Liaras K., Argyropoulou A., Geronikaki A., Sokovic M. (Greece)

Synthesis of non-substituted/substituted (E)-5-benzylidene-
2-(thiazol-2-ylamino)thiazol-4(5H)-ones as potent antibacterial agents

5

Melo T.R.F., Santos J.L., Vizioli E.O., Chelucci R.C., Chiquetto R., Chung M.C. (Brazil)

Design, synthesis and pharmacological evaluation of new analgesic/antiinflammatory 1,2,5-oxadiazole 2-oxide derivatives

6

Santos J.L., Lanaro C., Gambero S., Costa F.F., Lima L.M.,Cerecetto H., Vizioli E.O., Chung M.C. (Brazil)

Design, preparation and evaluation of thalidomide analogs for the sickle cell disease treatment

7

Savina S., Ruiz-Sanchis P., Acosta G., Cuevas C., Albericio F., Álvarez M. (Spain)

Isolation and synthesis of Mayotlide

8

Tanajev D., Lūsis V., Muceniece D. (Latvia)

Oxidative rearrangement of 5-oxo-1H-4,5-dihydroindeno[1,2-b]pyridines

9

Yakout E.M.A. (Egypt)

Synthesis of antimicrobial and antioxidant heterocycles, based on cyanoacetamide chemistry

10

Avetisyan N.G., Sirakanyan S.N., Paronikyan E.G., Noravyan A.S.,
Ovakimyan .A. (Armenia)

New amino derivatives of [1,2,4]triazolo[3,4-a][2,7]naphthyridines

11

Baranov D.S., Vasilevsky S.F. (Russia)

New heterocyclization of 1-acetylenyl-9,10-anthraquinones

12

Govdi A.I., Vasilevsky S.F., Sorokina I.V., Tolstikova T.G., Tolstikov G.A. (Russia)

The first representatives of acetylenic derivatives of betulonic acid

13

Berestovitskaya V.M., Baichurin R.I., Aboskalova N.I. (Russia)

Nitrocontaining 2,3-dihydro-1,5-benzothiazepines

14

Frolova T.V., Kim D.G. (Russia)

Bromo- and iodocyclization of 2-prenylthio-4(3H)pyrimidinones

15

Galaev A.I., Garazd M.M., Garazd Ya.L., Ogorodniichuk A.S. (Ukraine)

Synthesis of 6-heteroarylcoumarins

16

Gornostaev L.M., Dolgushina L.V., Halyavina Yu.G., Stashina G.A.,
Firgang S.I. (Russia)

The synthesis and base-catalyzed split of
1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione-2-oxides

17

Gubanova P.A., Ramsh S.M. (Russia)

Alkylation of 4,4'-dipyridyl

18

Kharitonov Yu.V., Shults E.E., lstikov G.. (Russia)

Palladium-catalyzed dehydrogenative coupling of labdanoid acid derivatives with various alkenes

19

Kozachenko A.P., Shablykin .V., Brovarets V.S. (Ukraine)

Synthesis of the new heterocyclic system
5,7,8,9-tetrahydroimidazo[1,2-][1,3]thiazolo[4,5-][1,3,2]diazaphosphinine

20

Nikitina Yu.A., Garazd M.M., Garazd Ya.L., Ogorodniichuk A.S. (Ukraine)

Synthesis and transformation of angular pyranoflavanones

 

 

18:0020:00 Sightseeing tour of channel of Saint-Petersburg

 

 


Thursday, August 5, 2010 (For Foreign Delegates)

 

 

9:0013:00 Peterhof

 

14:0015:00 Lunch

 

16:00 Social events for foreign quests (a visit to the Hermitage, entertainment program)

 

 

19:0020:30 Welcome Cocktail Party in the "N-Prospect"Art Gallery

 

 

 

Thursday, August 5, 2010
(Session
For Russian and CIS Delegates.
Working language is Russian)

(Oak Hall, Beloselsky-Belozersky Palace)

 

 

Plenary Lectures

 

Session Chairpersons: Prof. Mikhal'chuk A.L., Prof. Demchenko A.M.

10:0010:30

Chupakhin .N., Charushin V.N. (Russia)

SNH reactions in heterocyclic chemistry

10:3511:05

Granik V.G. (Russia)

New methodology of pyridine synthesis based on amide and lactam acetales employment

11:1011:40

Shklyaev Yu.V., Rozhkova Yu.S., Vshivkova T.C., Stryapunina O.G., KhmelevskayaK.A. (Russia)

Synthesis of partly hydrogenated nitrogen-containing heterocycles

 

Oral Presentation

11:4512:05

Laipanov R.K., Tokmakov G.P., Przheval'skii N.M. (Russia)

Grandberg synthesis of triptamines and its utilization in multicomponent reactions

 

12:1012:40 Coffee Break (State Dining Room, Beloselsky-Belozersky Palace)


 

Oral Presentations

 

Session Chairpersons: Prof. Granik V.G., Prof. Shklyaev Yu.V.

12:4513:05

Shults E.E., Bauman V.T., lstikov G.. (Russia)

Transition metal catalyzed reactions in the directed synthesis of pharmacological valuable derivatives of morphinane alkaloids

13:1013:30

Brovarets V.S., Pilyo S.G., Golovchenko A.V., Shablykin O.V.,
Kozachenko A.P., Prokopenko V.M.,Drach B.S. 
(Ukraine)

New transformations of 4,5-bifunctionally substituted derivatives of
1,3-oxazole

13:3513:55

Krasnov K.A., Kartsev V.G., Khrustalev V.N. (Russia)

Stereodirected T-reactions of barbituric acid derivatives

 

14:0015:25 Lunch

 

 

Oral Presentations

 

Session Chairpersons: Prof. Przheval'skii N.M., Prof. Shults E.E.

15:3015:50

Demchenko .., Kolesnikov .V., Lozynskii .. (Ukraine)

Condensed polymethyleneazoles

15:5516:15

Gulyakevich O.V., Mikhal'chuk A.L. (Belarus)

Transformations of the 2,3,4,6,7,11b,12,13-octahydro-
1-isoquino[2,1-a]-quinolin-1,13-diones and related azangular heterocycles in search and creation of new pharmacological agents

16:2016:40

Shikhaliev Kh.S., Stolpovskaya N.V., Krylskiy D.V., Liberman M.M.,
Levina A.M.
(Russia)

Heterocyclic systems based on substituted biguanides

16:4517:05

Sirakanyan S.N. (Armenia)

New derivatives of pyrido[3',2':4,5]tieno(furo)[3,2-d]pyrimidines

 


 

 

9:0018:00 Poster Session 2 (poster nos. 2136)

(The Gallery of Beloselsky-Belozersky Palace)

 

 

 

Poster nos.

Poster Details

21

Makarenko S.V., Stukan E.V., Berestovitskaya V.. (Russia)

1-Bromo-1-nitro-3,3,3-trichloropropene in synthesis of functionalized benzopyranes

22

Mikhailovskaya T.F., Vasilevsky S.F. (Russia)

Peculiarities of base-catalyzed intramolecular heterocyclization of hydrazides
ofbenzoic acids

23

Mikhal'chuk A.L., Gulyakevich O.V. (Belarus)

The structure and electronic absorption of α-aminovinyl-β-dicarbonyl compounds of the isoquino[2,1-a]quinoline series

24

Obukhova E.N., Tatarets A.L., Kolosova O.S., Fedyunyaeva I.A., Povrozin Ye.A., Patsenker L.D., Terpetschnig E.A. (Ukraine)

Synthesis and photophysical properties of unsymmetrical squarylium dyes based on sulfonated 3-indole and 1-benzo[]indole

25

Osyanin V.A., Ivleva E.A., Osipov D.V., Klimochkin Yu.N. (Russia)

Sterically hindered o-quinone methides in the synthesis of heterocycles

26

Palchikov V.A., Dulnev P.G., Shiyan V.S., Sviatenko L.K., Okovytyy S.I.,
Kasyan L.I. (Ukraine)

Experimental and theoretical study of aminolysis of 3,4-epoxysulfolane by bi- and polycyclic frame amines

27

Petrov A.A., Kasatochkin A.N., Emelina E.E. (Russia)

Regioselective synthesis of 5-trifluoromethyl-8,9-dihydro-
7H-pyrazolo[1,5-a]quinazolin-6-ones

28

Popilnichenko S.V., Kondratyuk K.M., Golovchenko A.V., Brovarets V.S. (Ukraine)

Newapproachesto synthesis of 4-phosphorylatedderivatives of 1,3-thiazole

29

Prokopenko V.M., Pilyo S.G., Brovarets V.S. (Ukraine)

Synthesisof 5-functionalizedderivatives of 4-heterylsubstituted 1,3-oxazoles

30

Ryzvanovich G.A., Begunov R.S. (Russia)

Synthesis of fused compounds of imidazole with bridgehead nitrogen atom

31

Serov A.B., Sukhotin A.V., Kartsev V.G. (Russia)

Indolylglycines in the 1,3-dipolar cycloaddition reactions

32

Serov A.B., Sukhotin A.V., Kartsev V.G. (Russia)

Substitution reactions on the third position of 3-acetamidoindolones-2

33

Sukhotin A.V., Serov A.B., Kartsev V.G. (Russia)

Synthesis of tetraoxopyrrolo[3.4-b]pyrroles

34

Sukhotin A.V., Serov A.B., Kartsev V.G. (Russia)

Spiroindolonopiperazinones

35

Surikova .V., Zachinyaeva .V., Mikhailovskii .G., Zachinyaev Ya.V., Vakhrina N.I. (Russia)

Synthesis, antibacterial and antifungal activity of benzo[f]isoquinoline's derivatives

36

Tatarets A.L., Fedyunyayeva I.A., Obukhova E.N., Povrozin Ye.A.,
Khabuseva S.U., Terpetschnig E.A., Patsenker L.D. (
Ukraine)

Synthesis, spectral properties and application of squaraines with substituted cyclobutenone oxygen atom

 

 

19:0020:30 Welcome Cocktail Party in the "N-Prospect"Art Gallery




Friday, August 6, 2010

 

(Oak Hall, Beloselsky-Belozersky Palace)


 

Plenary Lectures

 

Session Chairpersons: Prof. Rádl S., Prof. Chupakhin O.N.

10:0010:30

Pozharskii A.F., Povalyakhina M.A., Vlasenko M.P. (Russia)

Proton sponge-based heterocyclizations

10:3511:05

Bruno P., Just-Baringo X., Albericio F., Álvarez M. (Spain)

Total synthesis of natural products with heterocyclic structure

11:1011:40

Spagnolo P. (Italy)

Latest applications of aminyl and iminyl radicals derived from azides to the synthesis of nitrogen heterocycles

11:4512:15

Abu-Orabi S.T. (Jordan)

Utilization of 1,3-dipolar cycloaddition reaction of azides toward the synthesis of 5-membered heterocyclic compounds

 

12:2013:20 losing Ceremony

13:3014:00 Champagne Party (State Dining Room, Beloselsky-Belozersky Palace)

 

14:30 Departure